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Literature summary extracted from

  • Zhu, Y.; Jiang, X.; Wang, C.; Liu, Y.; Fan, X.; Zhang, L.; Niu, L.; Teng, M.; Li, X.
    Structural insights into the methyl donor recognition model of a novel membrane-binding protein UbiG (2016), Sci. Rep., 6, 23147 .
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.1.1.64 structure of UbiGDELTA165-187 in complex with SAH Escherichia coli
2.1.1.222 structure of UbiGDELTA165-187 in complex with SAH Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
2.1.1.64 additional information for mutant UbiGDELTA 165-187 lacking the sequence insertion that covers the methyl donor binding pocket, the binding affinity to SAH is approximately 58fold higher than that of wild-type Escherichia coli
2.1.1.222 additional information for mutant UbiGDELTA 165-187 lacking the sequence insertion that covers the methyl donor binding pocket, the binding affinity to SAH is approximately 58fold higher than that of wild-type Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.1.64 membrane the membrane-binding region of UbiG gates the entrance of methyl donor Escherichia coli 16020
-
2.1.1.222 membrane the membrane-binding region of UbiG gates the entrance of methyl donor Escherichia coli 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.64 Escherichia coli C3T302
-
-
2.1.1.222 Escherichia coli C3T302
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.64 S-adenosyl-L-methionine + 3-demethylubiquinol-n
-
 Escherichia coli S-adenosyl-L-homocysteine + ubiquinol-n
-
 ?
2.1.1.222 S-adenosyl-L-methionine + 3-(all-trans-polyprenyl)benzene-1,2-diol
-
 Escherichia coli S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-polyprenyl)phenol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.64 UbiG
-
 Escherichia coli
2.1.1.64 ubiquinone biosynthesis O-methyltransferase
-
 Escherichia coli
2.1.1.222 UbiG
-
 Escherichia coli
2.1.1.222 ubiquinone biosynthesis O-methyltransferase
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
2.1.1.64 physiological function the membrane-binding region of UbiG gates the entrance of methyl donor. When bound with liposome, UbiG displays an enhanced binding ability toward the methyl donor product S-adenosylhomocysteine Escherichia coli
2.1.1.222 physiological function the membrane-binding region of UbiG gates the entrance of methyl donor. When bound with liposome, UbiG displays an enhanced binding ability toward the methyl donor product S-adenosylhomocysteine Escherichia coli